Iowa State continued its early-season Big 12 struggles Saturday with an 87-54 loss at No. 14 Missouri.

The Cyclones (14-6, 1-4 Big 12), playing their second-consecutive conference game on the road, and their tired legs were evident from the tip. Iowa State shot just 19-of-70 from the field, a measly 27 percent.

Missouri (17-3, 3-2) on the other hand, shot 43 percent, including hitting on 10 of its 29 3-point tries.

The Cyclones scored the game’s first points, but the 2-0 advantage would be their only lead. The game was as close as a four-point Missouri lead midway through the first half, but the Tigers would stretch the lead out to 48-26 at intermission before taking the 33-point victory.

This was the Cyclones’ first loss by double digits and the worst loss for first-year coach Fred Hoiberg. The previous worst loss came Wednesday, a nine-point loss at Oklahoma State. Iowa State has now lost four of its last five games. 

Jake Anderson led the Cyclones with 20 points, the only ISU player to reach double digits. All five Missouri starters scored in double figures.

Iowa State now moves on to face two of the Big 12’s worst performers in 2011, Texas Tech on Wednesday and Oklahoma on Saturday. Both games will take place at Hilton Coliseum.