Reggie McNeal passed for 222 yards and three touchdowns and ran for another score to lead surging Texas A&M to a 34-3 victory over Iowa State on Saturday night.

With its fourth straight win, A&M (4-1, 2-0 Big 12) matched last season’s victory total and handed Iowa State its 12th consecutive conference loss. The Cyclones (2-3, 0-2) have lost those games by an average of 33 points.

McNeal gave Iowa State fits all night with his accurate throwing and nimble feet. He scrambled out of trouble on several occasions and finished 16-for-27 with no interceptions and touchdown passes of 18 yards to Tydrick Riley, 13 yards to Joey Thomas and 12 yards to Courtney Lewis.

His most impressive footwork came early in a 13-play, 96-yard scoring drive that gave the Aggies a 20-3 halftime lead. On second-and-21 from his own 4, McNeal danced away from three Iowa State defenders who had a shot at him in the end zone and completed a 23-yard pass to Jason Carter.

McNeal went on to complete seven straight passes in taking A&M to the Iowa State 22. Lewis then sprinted 20 yards up the middle before McNeal slipped untouched into the end zone from the 2.

Any chance Iowa State had of getting back into it ended on the first play of the second half. Mike Montgomery intercepted Austin Flynn’s pass and returned it 14 yards to the ISU 17.

An illegal block in the back nullified Lewis’ 13-yard touchdown run, but it didn’t matter because the Aggies scored on the next play. McNeal floated a short pass to Lewis in the right flat and two defenders missed tackles on the 12-yard scoring play that made it 27-3.

Iowa State’s starting quarterback, Bret Meyer, was hit hard at the end of the second quarter and did not play in the second half. By the time A&M scored its final touchdown on reserve Ty Branyon’s 8-yard pass to DeQawn Mobley with 5:59 left, long lines of cars were leaving the stadium parking lots in all directions, their red tail light glowing brightly in the night.

McNeal gave Iowa State’s defenders an indication of what they’d be facing on the game’s first play. He started to his right on a keeper, saw three ISU players blocking his path, reversed field and ran 19 yards around left end.

That started a seven-play, 56-yard drive that McNeal finished with his touchdown pass to Riley, who caught the ball on a crossing pattern and dragged safety Steve Paris into the end zone.

Iowa State appeared to make the first interception of the season off McNeal when Nik Moser picked off a pass in the end zone on A&M’s next possession. But a pass- interference call against defensive back LaMarcus Hicks, who was 15 yards from the ball, gave the Aggies another chance.

Two plays later, McNeal rolled to his right, dumped the ball to Thomas at the 10 and the 6-foot-5, 243-yard freshman took it the rest of the way.