For the second time this season, the ISU men’s basketball team held a lead for much of the game but eventually fell to No. 7 Missouri 78-72.

The Cyclones (21-9, 11-6 Big 12) led by as many as seven points in the second half, but weren’t able to finish off the Tigers (26-4, 13-4), who guaranteed themselves at least a No. 2 seed in the Big 12 tournament.

While Iowa State outshot Missouri from 3-point range (40 to 33.3 percent) and outrebounded the Tigers 32-26, the Cyclones committed 15 turnovers in the game.

Iowa State was led offensively by forward Royce White, who finished the game with 20 points, nine assists and six rebounds.

The Cyclones’ final regular-season game is Saturday.